Retracted autism study an 'elaborate fraud,' British journal finds

By the CNN Wire Staff
January 5, 2011 7:11 p.m. EST
Dr. Andrew Wakefield misrepresented or altered medical histories to bolster his 1998 study, an investigation found

(CNN) -- A now-retracted British study that linked autism to childhood vaccines was an "elaborate fraud" that has done long-lasting damage to public health, a leading medical publication reported Wednesday.

An investigation published by the British medical journal BMJ concludes the study's author, Dr. Andrew Wakefield, misrepresented or altered the medical histories of all 12 of the patients whose cases formed the basis of the 1998 study -- and that there was "no doubt" Wakefield was responsible.

"It's one thing to have a bad study, a study full of error, and for the authors then to admit that they made errors," Fiona Godlee, BMJ's editor-in-chief, told CNN. "But in this case, we have a very different picture of what seems to be a deliberate attempt to create an impression that there was a link by falsifying the data."

Britain stripped Wakefield of his medical license in May 2010. Efforts to reach him for comment were unsuccessful Wednesday.

"Meanwhile, the damage to public health continues, fueled by unbalanced media reporting and an ineffective response from government, researchers, journals and the medical profession," BMJ states.

The now-discredited paper panicked many parents and led to a sharp drop in the number of children getting the vaccine that prevents measles, mumps and rubella. Vaccination rates dropped sharply in Britain after its publication, falling as low as 80 percent by 2004. Measles cases have gone up sharply in the ensuing years.

In the United States, more cases of measles were reported in 2008 than in any other year since 1997, according to the Centers for Disease Control and Prevention. More than 90 percent of those infected had not been vaccinated or their vaccination status was unknown, the CDC reported.

"But perhaps as important as the scare's effect on infectious disease is the energy, emotion and money that have been diverted away from efforts to understand the real causes of autism and how to help children and families who live with it," the BMJ editorial states.

Wakefield has been unable to reproduce his results in the face of criticism, and other researchers have been unable to match them. Most of his co-authors withdrew their names from the study in 2004 after learning he had had been paid by a law firm that intended to sue vaccine manufacturers -- a serious conflict of interest he failed to disclose. After years on controversy, the Lancet, the prestigious journal that originally published the research, retracted Wakefield's paper last February.

Unfortunately, (Wakefield's) core group of supporters is not going to let the facts dissuade their beliefs that MMR causes autism.
--Dr. Max Wiznitzer, pediatric neurologist

The series of articles launched Wednesday are investigative journalism, not results of a clinical study. The writer, Brian Deer, said Wakefield "chiseled" the data before him, "falsifying medical histories of children and essentially concocting a picture, which was the picture he was contracted to find by lawyers hoping to sue vaccine manufacturers and to create a vaccine scare."

According to BMJ, Wakefield received more than 435,000 pounds ($674,000) from the lawyers. Godlee said the study shows that of the 12 cases Wakefield examined in his paper, five showed developmental problems before receiving the MMR vaccine and three never had autism.

"It's always hard to explain fraud and where it affects people to lie in science," Godlee said. "But it does seem a financial motive was underlying this, both in terms of payments by lawyers and through legal aid grants that he received but also through financial schemes that he hoped would benefit him through diagnostic and other tests for autism and MMR-related issues."

Dr. Max Wiznitzer, a pediatric neurologist at Rainbow Babies & Children's Hospital in Cleveland, said the reporting "represents Wakefield as a person where the ends justified the means." But he said the latest news may have little effect on those families who still blame vaccines for their children's conditions.

"Unfortunately, his core group of supporters is not going to let the facts dissuade their beliefs that MMR causes autism," Wiznitzer said. "They need to be open-minded and examine the information as everybody else."

Wakefield's defenders include David Kirby, a journalist who has written extensively on autism. He told CNN that Wakefield not only has denied falsifying data, he has said he had no way to do so.

"I have known him for a number of years. He does not strike me as a charlatan or a liar," Kirby said. If the BMJ allegations are true, then Wakefield "did a terrible thing" -- but he added, "I personally find it hard to believe that he did that."

CNN's Elizabeth Cohen and Miriam Falco contributed to this report.

http://www.cnn.com/2011/HEALTH/01/05/autism.vaccines/index.html?hpt...

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icon Autism


On May 11, 2002 and again on Dec 14, 2005 the Zetas stated that the rise in autism was not due to vaccinations but an adjustment to the increasing tensions in the world due to the Earth changes and the pending pole shift.

Why the upsurge in autism in recent years, in parallel with the mercury in vaccines? Where the evidence against pharmaceutical companies and the government agencies leaned on to exclude any data that would pave the way for litigation against them in no way makes them heroes, here the link is not failsafe. If the vaccine melts the brain of a child, then why have all such children so vaccinated between 1989 and 2003 been so affected? What else has been on the rise since 1989? Beaching whales; mad cow disease and the wildlife equivalent, a wasting disease; dead fish washing up on beaches; the red tide, an algae bloom; flesh eating bacteria; chronic fatigue syndrome; depression among adults; suicide among children; adults and teens going postal and murdering their families and then themselves.
ZetaTalk: Autism Rise, writen May 11, 2002

On May 4, 2006 Reuters reported that Autism was indeed on the increased, steadily so, rising between 1996 and 1998, and stating of the vaccine link that 'studies in several countries have discounted such a link.' Autism is on the rise even where vacinations are not occurring.

US Survey Shows Autism Very Common
May 4, 2006
http://today.reuters.com/
The first national surveys of autism show the condition is very common among U.S. children - with up to one in every 175 with the disorder, the U.S. Centers for Disease Control and Prevention said on Thursday. The 1996 Metropolitan Atlanta Developmental Disabilities Surveillance Program survey showed autism had been diagnosed in 3.4 per 1,000 of the 3- to 10-year-olds included, or one in every 296. The 1998 Brick Township, New Jersey survey showed a rate of 6.7 per 1,000 children of the same age, or one in every 166. None of the surveys pointed to a cause for autism -- a matter of deep controversy in the United States. Some groups have accused the CDC of covering up data that would link autism with vaccines, although studies in several countries have discounted such a link. Both surveys indicated that boys were nearly four times more likely to have been diagnosed with autism than girls. Both surveys indicated that Hispanic children were less likely to have an autism diagnosis.

On January 1, 2008 results showed that autism has increased steadily even as mercury in vaccinations has dropped, a reverse of what was expected.

Research Reaffirms: No Vaccine-Autism Link
January 1, 2008
http://abcnews.go.com/Health/story?id=4099059&page=1
A new study may be the latest nail in the coffin of a theory that draws a link between the mercury-containing vaccine additive thimerosal and autism. The research is the latest to contradict concerns over childhood vaccinations as a possible cause of autism -- concerns that have gained publicity in the past decade as the number of children diagnosed with the disorder climbs steadily in the United States. Because vaccinations are mandatory for all children at a certain age, some parents and doctors believe that the mercury once found in many childhood vaccines may contribute to the development of autism. However, so far a number of large scientific studies have shown no association between thimerosal and autism. And the most recent research to nullify this association, published Monday in the journal Archives of General Psychiatry, reveals that the prevalence of autism for children ages 3 to 12 continued to increase in California even after 2001 -- when all but trace levels of mercury had been removed from most childhood vaccines.

In July 1999, the U.S. Public Health Service implemented a precautionary measure removing thimerosal -- which contains 49.6 percent ethylmercury -- from all childhood vaccines. To determine whether reduced exposure to thimerosal led to a decrease in autism cases, researchers at the California Department of Public Health analyzed data from the California Department of Developmental Services on the prevalence by age and birth cohort of children with autism between 1995 and 2007. But instead of finding a decrease in autism following the elimination of thimerosal from most vaccines, researchers found that for each quarter from 1995 to the end of 2003, the prevalence of autism in children between the ages of 3 and 5 years increased from 0.6 to 2.9 per 1,000 births. From 2004 to 2007, when exposure to thimerosal from childhood vaccinations vastly declined, the prevalence of autism in children between the ages of 3 and 5 years increased from 3.0 to 4.1 per 1,000 births. The findings bolster the position that has been steadfastly held by the Institute of Medicine, and many doctors worldwide, that no link can be established between thimerosal and autism. Some researchers say that the absence of a link has already been demonstrated in Denmark, where thimerosal was removed from all vaccines in 1992. Despite this move, autism rates in that country continued to rise until 2004.

Yet another 2008 article states that genetic links to autism have been noted.

Chromosome Abnormality Linked to Autism
Jan 9, 2008
http://www.businessweek.com/technology/content/jan2008/
The abnormalities were linked with certainty to only 1% of autism cases. Using a very large genome scan, the researchers also discovered that the genetic abnormalities-either a deletion or a duplication of a section of chromosome 16-were not directly inherited from either parent. Instead they developed spontaneously during the embryonic stage of development, possibly due to interplay of various genetic factors inherited from the parents. Autism spectrum disorder, as it is formally known, is a profound developmental disease that affects speech, behavior, and cognition. Doctors know the disease runs in families-90% of cases may be genetic-but the genetic pathways have been extremely difficult to identify, likely because more than one is the culprit. Only in 10% of cases can it be linked to specific and well-known genetic anomalies, such as fragile-X syndrome.


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ZetaTalk: Autism Rise
Note: writen during the May 11, 2002 Live ZetaTalk IRC Session


Autism on the rise is not a manmade affliction nor related. This increase is related to inbreeding, among those with similar propensities. Obsessive individuals do not feel comfortable among those with high emotions and spontaneity. They bond, befriend, and spend time with others who like a regimented life style. Repeatedly intermarrying, this then becomes a dominate gene, and expresses.

Additional ZetaTalk added Dec 14, 2005.

Why is the evidence against mercury so high, so low as to be almost absent in the Amish and children being schooled at home as their parents want to avoid the vaccination requirements for entry into the school system and the like? Why the upsurge in autism in recent years, in parallel with the mercury in vaccines? Where the evidence against pharmaceutical companies and the government agencies leaned on to exclude any data that would pave the way for litigation against them in no way makes them heroes, here the link is not failsafe. If the vaccine melts the brain of a child, then why have all such children so vaccinated between 1989 and 2003 been so affected?

What else has been on the rise since 1989? Beaching whales; mad cow disease and the wildlife equivalent, a wasting disease; dead fish washing up on beaches; the red tide, an algae bloom; flesh eating bacteria; chronic fatigue syndrome; depression among adults; suicide among children; adults and teens going postal and murdering their families and then themselves. What factors can affect this?

  1. a global recession, in fact an economic depression, emerging by the year 2000 as Bush took the White House but denied in the media
  2. the approach of Planet X which began in 1995 and entry into the inner solar system in the year 2003
  3. a cover-up so complete that no discussion of Earth changes is allowed to explain matters to a public aware that even the reliable Moon is out of orbit regularly
  4. a disturbed core of the Earth roiling such that the White Buffalo and other albinos began appearing increasingly

All of this affecting the psyche and immune systems of humans. What effect does this have on human interactions? Job loss and bankruptcies stress the wage earner and his or her family alike. Marital harmony is stressed. Couples wanting children find themselves unable to conceive. Fathers find their confidence in being a protector of the family challenged, and mothers wanting a secure environment for their newborns and young find themselves tense. Children reflect the environment they find themselves in, and even those homes supposedly sheltered from the buffeting of economic problems sense the shape the world is in. The parents are tense, the child withdraws, and this is all symptomatic of the stress the parents are under. If the issue of why the Earth changes are occurring, and what people can do about helping themselves, were openly discussed, this would ease as direct action against the real issues would occur. But instead, due to the cover-up, the public is told to carry on, march in place as though nothing were wrong, and this is the real culprit in the autism increase.

Additional ZetaTalk added Dec 3, 2007

Autism, as childhood schizophrenia, has the brain chemistry affected, just as adult schizophrenia does - an excess of this chemical, a lack of that chemical, etc. Just as the homosexual lifestyle can affect the brain development, can affect the hormones released, the decision by the child's body to be insane, to withdraw, can affect the developing child's brain, which is so very plastic. Fever disturbs chemical relationships, chemical bonds, breaking them and thus allowing normal brain development for a time. Regular heat treatments may result in the treatment of autistic children, in an attempt to change the course of the disease, but this will prove futile in most cases.

That auto-immune factors have been found in some mothers, where their bodies are attacking the fetus brain, is not surprising, as in autism cases the mothers are often tense, under stress, the setting that causes childhood schizophrenia in the first place. Auto-immune disease is due to a heightened immune system, as allergies are, so the fact that the mother is reacting to what her body might consider a foreign substance from the fetus is not surprising. This reaction in the mother can also teach the fetus to react in a similar fashion. The fetus brain cells, attacked, break down into pieces, each viewed by the developing fetus as a foreign substance as the clues that the cell is whole are missing, disrupted.

Fever can unlock autism's grip: study
Dec 3, 2007
http://www.reuters.com/article/healthNews/idUSN2921232720071203?
It appears that fever restores nerve cell communications in regions of the autistic brain, restoring a child's ability to interact and socialize during the fever. The study, published in the journal Pediatrics, was based on 30 children with autism aged 2 to 18 who were observed during and after a fever of at least 100.4 degrees Fahrenheit. The change involved things like longer concentration spans, more talking, improved eye contact and better overall relations with adults and other children.
  
Autoimmune Theories
http://www.healing-arts.org/children/autism-overview.htm#Autoimmune
Brain autoantibodies to myelin basic protein (anti-MBP) and neuron-axon filament protein (anti-NAFP) have been found in autistic children. Immunological testing of autistic children has shown certain features that are also found in patients with autoimmune diseases such as systemic lupus erythematosus, thyroid disease, ankylosing spondylitis, rheumatoid arthritis, insulin-dependent diabetes, and multiple sclerosis. These are: genetic predisposition -- autism shows a greater concordance rate in monozygotic twins than in the normal population; gender factor - autism is 4 or 5 times more common in boys than in girls; triggering by microorganisms - rubella virus and cytomegalovirus infections have been indirectly linked to autism; maternal factors --maternal antibodies in autism were detected; (e ) major histocompatibility association -- autism displays genetic linkage with immunogenetic factors located on chromosome six; and immune activation.
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